Monte carlo based performance assessment of four commercial GE discovery PET scanners using GATE

P. Geramifar, M. R. Ay, M. Shamsaie, G. Loudos, A. Rahmim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Combined PET/CT scanners now playa major role in medicine for in vivo imaging in oncology, cardiology, neurology, and psychiatry. As the performance of a scanner depends not only on the scintillating material but also on the scanner design, with regards to the advent of newer scanners, there is a need to optimize acquisition protocols as well as to compare scanner performances on an objective basis. In this study we evaluate and compare the performance of four Commercial GE PET/CT cameras, the (i) BGO-based Discovery LS PET/CT (DLS), (ii) the BGO-based Discovery ST PET/CT (DST), (iii) the BGO-based Discovery STE PET/CT (DSTE) and finally (iv) the LYSO-based Discovery RX PET/CT (DRX) scanner using the Geant4 Application for Tomographic Emission (GATE) Monte Carlo code. GATE is an open source Monte Carlo simulation platform mostly developed for PET and SPECT studies and is supported by the OpenGATE coUaboration. In accordance with the National Electrical Manufactures Association (NEMA) NU 2-2001 protocols, the validation of models is carried out against actual published measurements and the performance comparison is done for sensitivity, scatter fraction and count rate performance, showing very similar performance compared with published results, thus enabling investigations to better model system performance (e.g. resolution degradation) within the reconstruction task. The simulated results demonstrate highest sensitivity performance with the DST (though with the highest scatter fraction), and highest NECR performance for the LYSO-based DRX, The results also show that DRX, DLS and DSTE PET/CT cameras have nearly the same amount of scatter fraction.

Original languageEnglish (US)
Title of host publication2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Pages3995-3999
Number of pages5
DOIs
StatePublished - Dec 1 2008
Event2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008 - Dresden, Germany
Duration: Oct 19 2008Oct 25 2008

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Other

Other2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Country/TerritoryGermany
CityDresden
Period10/19/0810/25/08

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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