Abstract
A 3.5 year old boy with X-linked severe combined immunodeficiency disease (SCID), who had been in laminar flow isolation throughout his life, developed a B cell tumour producing up to 3008 mg/dl of an IgM(k) paraprotein 1 month after infusion of both liver and thymus cells from a fetal donor and 6 months after the last of six fetal liver cell infusions given over a 3 year period. Pretransplant studies revealed a high percentage of circulating B lymphocytes. HLA typing suggests that the tumour was of host origin.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 666-674 |
| Number of pages | 9 |
| Journal | Clinical and Experimental Immunology |
| Volume | 48 |
| Issue number | 3 |
| State | Published - 1982 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
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Shirley, L. R., Buckley, R. H., Borowitz, M. J., Welt, S. I., & Kostyu, D. D. (1982). Monoclonal immunoglobulin-secreting lymphoma in a patient with severe combined immunodeficiency disease. Clinical and Experimental Immunology, 48(3), 666-674.