Abstract
A 3.5 year old boy with X-linked severe combined immunodeficiency disease (SCID), who had been in laminar flow isolation throughout his life, developed a B cell tumour producing up to 3008 mg/dl of an IgM(k) paraprotein 1 month after infusion of both liver and thymus cells from a fetal donor and 6 months after the last of six fetal liver cell infusions given over a 3 year period. Pretransplant studies revealed a high percentage of circulating B lymphocytes. HLA typing suggests that the tumour was of host origin.
Original language | English (US) |
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Pages (from-to) | 666-674 |
Number of pages | 9 |
Journal | Clinical and Experimental Immunology |
Volume | 48 |
Issue number | 3 |
State | Published - 1982 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology