Monitoring of intestinal transplant rejection

Daniel H. Teitelbaum; William E. Wise; Roberta E. Sonnino; David J. Dunaway; Priscilla Powers; H. Juhling McClung; Richard P. Harmel

doi:10.1016/0002-9610(89)90561-8

Monitoring of intestinal transplant rejection

Daniel H. Teitelbaum, William E. Wise, Roberta E. Sonnino, David J. Dunaway, Priscilla Powers, H. Juhling McClung, Richard P. Harmel

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Our results show that maltase, sucrase, and lactase activity are present at a normal level in nonrejecting small bowel transplants after an initial postoperative decline. This confirms that the disaccharide absorbing capacity of these grafts is intact. In allogeneic bowel, however, the levels of maltase and sucrase decline as histologic rejection occurs. These results suggest that serial maltase, sucrase, and possibly lactase levels in allogeneic intestinal transplants may serve as a useful adjunct in the monitoring of small bowel transplant rejection.

Original language	English (US)
Pages (from-to)	318-322
Number of pages	5
Journal	The American Journal of Surgery
Volume	157
Issue number	3
DOIs	https://doi.org/10.1016/0002-9610(89)90561-8
State	Published - Mar 1989
Externally published	Yes

ASJC Scopus subject areas

Surgery

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10.1016/0002-9610(89)90561-8

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title = "Monitoring of intestinal transplant rejection",

abstract = "Our results show that maltase, sucrase, and lactase activity are present at a normal level in nonrejecting small bowel transplants after an initial postoperative decline. This confirms that the disaccharide absorbing capacity of these grafts is intact. In allogeneic bowel, however, the levels of maltase and sucrase decline as histologic rejection occurs. These results suggest that serial maltase, sucrase, and possibly lactase levels in allogeneic intestinal transplants may serve as a useful adjunct in the monitoring of small bowel transplant rejection.",

author = "Teitelbaum, {Daniel H.} and Wise, {William E.} and Sonnino, {Roberta E.} and Dunaway, {David J.} and Priscilla Powers and McClung, {H. Juhling} and Harmel, {Richard P.}",

note = "Funding Information: From the Division of Pediatric Surgery, Children{\textquoteright}s Hospital and the Departments of Surgery -_ and Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio. Supported in part by Grant ROi-DK36061 from the National Insitutes of Health. Bethesda. Marvland.",

year = "1989",

month = mar,

doi = "10.1016/0002-9610(89)90561-8",

language = "English (US)",

volume = "157",

pages = "318--322",

journal = "The American Journal of Surgery",

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TY - JOUR

T1 - Monitoring of intestinal transplant rejection

AU - Teitelbaum, Daniel H.

AU - Wise, William E.

AU - Sonnino, Roberta E.

AU - Dunaway, David J.

AU - Powers, Priscilla

AU - McClung, H. Juhling

AU - Harmel, Richard P.

N1 - Funding Information: From the Division of Pediatric Surgery, Children’s Hospital and the Departments of Surgery -_ and Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio. Supported in part by Grant ROi-DK36061 from the National Insitutes of Health. Bethesda. Marvland.

PY - 1989/3

Y1 - 1989/3

N2 - Our results show that maltase, sucrase, and lactase activity are present at a normal level in nonrejecting small bowel transplants after an initial postoperative decline. This confirms that the disaccharide absorbing capacity of these grafts is intact. In allogeneic bowel, however, the levels of maltase and sucrase decline as histologic rejection occurs. These results suggest that serial maltase, sucrase, and possibly lactase levels in allogeneic intestinal transplants may serve as a useful adjunct in the monitoring of small bowel transplant rejection.

AB - Our results show that maltase, sucrase, and lactase activity are present at a normal level in nonrejecting small bowel transplants after an initial postoperative decline. This confirms that the disaccharide absorbing capacity of these grafts is intact. In allogeneic bowel, however, the levels of maltase and sucrase decline as histologic rejection occurs. These results suggest that serial maltase, sucrase, and possibly lactase levels in allogeneic intestinal transplants may serve as a useful adjunct in the monitoring of small bowel transplant rejection.

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Monitoring of intestinal transplant rejection

Abstract

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