Molecular Toggle Switch of Histone Demethylase LSD1

Jaehoon Shin, Guo li Ming, Hongjun Song

Research output: Contribution to journalArticle

Abstract

In this issue of Molecular Cell, Laurent etal. (2015) demonstrated that a neuron-enriched isoform of LSD1 (LSD1+8a) within a SVIL-containing complex exhibits H3K9me1/2-specific demethylation activity. Such activity was crucial for gene activation during mammalian neurogenesis. In this issue of Molecular Cell, Laurent etal. (2015) demonstrated that a neuron-enriched isoform of LSD1 (LSD1+8a) within a SVIL-containing complex exhibits H3K9me1/2-specific demethylation activity. Such activity was crucial for gene activation during mammalian neurogenesis.

Original languageEnglish (US)
Pages (from-to)949-950
Number of pages2
JournalMolecular Cell
Volume57
Issue number6
DOIs
StatePublished - Mar 19 2015

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Histone Demethylases
Neurogenesis
Transcriptional Activation
Protein Isoforms
Neurons

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology
  • Medicine(all)

Cite this

Molecular Toggle Switch of Histone Demethylase LSD1. / Shin, Jaehoon; Ming, Guo li; Song, Hongjun.

In: Molecular Cell, Vol. 57, No. 6, 19.03.2015, p. 949-950.

Research output: Contribution to journalArticle

Shin, Jaehoon ; Ming, Guo li ; Song, Hongjun. / Molecular Toggle Switch of Histone Demethylase LSD1. In: Molecular Cell. 2015 ; Vol. 57, No. 6. pp. 949-950.
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