Hypoxia-regulated genes play an important role in ocular neovascularization and macular edema. VEGF is particularly important and most efforts thus far have been directed at suppressing VEGF. Over the next several years agents that target other hypoxia-regulated gene products will be tested in combination with VEGF antagonists to see if additional benefit can be obtained.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Jul 1 2010|
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