Molecular structure of a double helical DNA fragment intercalator complex between deoxy CpG and a terpyridine platinum compound

Andrew H.J. Wang, Jeremy Nathans, G. Van Der Marel, J. H. Van Boom, Alexander Rich

Research output: Contribution to journalArticle

Abstract

The crystal structure of a complex containing deoxy CpG and a terpyridine platinum compound (TPH) shows a DNA double helical fragment with TPH intercalated between two Watson-Crick GC base pairs. The DNA unwinding angle is 23° and the pucker of the deoxyribose rings differ at the 3′ and 5′ ends.

Original languageEnglish (US)
Pages (from-to)471-474
Number of pages4
JournalNature
Volume276
Issue number5687
DOIs
StatePublished - Dec 1 1978
Externally publishedYes

ASJC Scopus subject areas

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