Molecular pathways in pancreatic carcinogenesis

Anne M. MacGregor-Das, Christine A. Iacobuzio-Donahue

Research output: Contribution to journalArticle

Abstract

Pancreatic cancer is a genetic disease. Pancreatic cancers develop from one of three precursor lesions, pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasms (IPMNs), and mucinous cystic neoplasms (MCNs), and each arises in association with distinct genetic alterations. These alterations not only provide insight into the fundamental origins of pancreatic cancer but provide ample opportunity for improving early diagnosis and management of cystic precursors. J. Surg. Oncol. 2013;107:8-14.

Original languageEnglish (US)
Pages (from-to)8-14
Number of pages7
JournalJournal of Surgical Oncology
Volume107
Issue number1
DOIs
StatePublished - Jan 2013

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Pancreatic Neoplasms
Carcinogenesis
Neoplasms
Inborn Genetic Diseases
Early Diagnosis

Keywords

  • cystic neoplasm
  • GNAS
  • pancreatic cancer
  • RNF43

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

MacGregor-Das, A. M., & Iacobuzio-Donahue, C. A. (2013). Molecular pathways in pancreatic carcinogenesis. Journal of Surgical Oncology, 107(1), 8-14. https://doi.org/10.1002/jso.23213

Molecular pathways in pancreatic carcinogenesis. / MacGregor-Das, Anne M.; Iacobuzio-Donahue, Christine A.

In: Journal of Surgical Oncology, Vol. 107, No. 1, 01.2013, p. 8-14.

Research output: Contribution to journalArticle

MacGregor-Das, AM & Iacobuzio-Donahue, CA 2013, 'Molecular pathways in pancreatic carcinogenesis', Journal of Surgical Oncology, vol. 107, no. 1, pp. 8-14. https://doi.org/10.1002/jso.23213
MacGregor-Das, Anne M. ; Iacobuzio-Donahue, Christine A. / Molecular pathways in pancreatic carcinogenesis. In: Journal of Surgical Oncology. 2013 ; Vol. 107, No. 1. pp. 8-14.
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