Molecular modeling and in vitro investigations of the human androgen receptor DNA-binding domain: Application for the study of two mutations

Medicine & Life Sciences

• human AR protein 100%
• Androgen Receptors 71%
• Androgens 45%
• Mutation 37%
• DNA 36%
• Amino Acid Substitution 35%
• In Vitro Techniques 28%
• Protein Multimerization 25%
• 1,2-diamino-1,2-N,N'-carbonyl-1,2-dideoxyglucose hydrate 24%
• Androgen-Insensitivity Syndrome 24%
• Valine 19%
• Glucocorticoid Receptors 18%
• Proteins 18%
• Phenylalanine 18%
• Electrophoretic Mobility Shift Assay 18%
• Site-Directed Mutagenesis 17%
• Proline 17%
• Leucine 16%
• Reporter Genes 16%
• Point Mutation 16%
• Western Blotting 11%
• Genes 6%

Chemical Compounds

• Androgen 83%
• Molecular Modeling 59%
• Mutation 55%
• Application 20%
• Glucocorticoid 10%
• Substitution Reaction 10%
• Protein 10%
• Valine 9%
• Leucine 8%
• Site-Directed Mutagenesis 8%
• Proline 8%
• Phenylalanine 8%
• Protein Structure 8%
• Dimerization 7%
• Acid 5%