Molecular mechanisms of human papillomavirus-related carcinogenesis in head and neck cancer

Farhoud Faraji, Munfarid Zaidi, Carole Fakhry, Daria A. Gaykalova

Research output: Contribution to journalArticlepeer-review

Abstract

This review examines the general cellular and molecular underpinnings of human papillomavirus (HPV)-related carcinogenesis in the context of head and neck squamous cell carcinoma (HNSCC) and focuses on HPV-positive oropharyngeal squamous cell carcinoma in areas for which specific data is available. It covers the major pathways dysregulated in HPV- positive HNSCC and the genome-wide changes associated with this disease.

Original languageEnglish (US)
JournalUnknown Journal
DOIs
StatePublished - May 16 2017

Keywords

  • chromatin
  • HNSCC
  • HPV
  • oropharyngeal
  • squamous cell carcinoma
  • viral integration

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • Immunology and Microbiology(all)
  • Neuroscience(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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