Molecular mechanisms of human papillomavirus-related carcinogenesis in head and neck cancer

Farhoud Faraji, Munfarid Zaidi, Carole Fakhry, Daria Gaykalova

Research output: Contribution to journalArticle

Abstract

This review examines the general cellular and molecular underpinnings of human papillomavirus (HPV)-related carcinogenesis in the context of head and neck squamous cell carcinoma (HNSCC) and focuses on HPV-positive oropharyngeal squamous cell carcinoma in areas for which specific data is available. It covers the major pathways dysregulated in HPV-positive HNSCC and the genome-wide changes associated with this disease.

Original languageEnglish (US)
JournalMicrobes and Infection
DOIs
StateAccepted/In press - 2017

Keywords

  • Chromatin
  • HNSCC
  • HPV
  • Oropharyngeal
  • Squamous cell carcinoma
  • Viral integration

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

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