Molecular genetics of exocrine pancreatic neoplasms

S. A. Hahn, S. E. Kern

Research output: Contribution to journalArticle

Abstract

Molecular genetic studies of pancreatic ductal adenocarcinoma have revealed the common co-existence of K-ras, p53, and MTS1 mutations. The finding of K-ras mutations in epithelial lesions of ducts suggests them as a precursor intraepithelial neoplasm. The clinical importance of this line of work can only be anticipated at present, and a fuller understanding of genetic alterations in these neoplasms is necessary.

Original languageEnglish (US)
Pages (from-to)857-869
Number of pages13
JournalSurgical Clinics of North America
Volume75
Issue number5
DOIs
StatePublished - Jan 1 1995

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ASJC Scopus subject areas

  • Surgery

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