Molecular genetics of exocrine pancreatic neoplasms

S. A. Hahn, Scott E Kern

Research output: Contribution to journalArticle

Abstract

Molecular genetic studies of pancreatic ductal adenocarcinoma have revealed the common co-existence of K-ras, p53, and MTS1 mutations. The finding of K-ras mutations in epithelial lesions of ducts suggests them as a precursor intraepithelial neoplasm. The clinical importance of this line of work can only be anticipated at present, and a fuller understanding of genetic alterations in these neoplasms is necessary.

Original languageEnglish (US)
Pages (from-to)857-869
Number of pages13
JournalThe Surgical clinics of North America
Volume75
Issue number5
StatePublished - 1995

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Pancreatic Neoplasms
Molecular Biology
Mutation
Carcinoma in Situ
Adenocarcinoma
Neoplasms

ASJC Scopus subject areas

  • Surgery

Cite this

Molecular genetics of exocrine pancreatic neoplasms. / Hahn, S. A.; Kern, Scott E.

In: The Surgical clinics of North America, Vol. 75, No. 5, 1995, p. 857-869.

Research output: Contribution to journalArticle

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