@article{8235c36ef5c5439486eda349e3d01c8d,
title = "Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch",
abstract = "C-fiber tactile afferents are a subpopulation of unmyelinated cutaneous sensory neurons activated by gentle stroking. Using a genetically encoded tracer, we found that Mas-related G protein-coupled receptor B4 marks a rare subpopulation of unmyelinated, nonpeptidergic sensory fibers that exclusively innervate hairy skin. These fibers terminate in large arborizations similar in size and distribution to C-fiber tactile afferent receptive fields, suggesting that MrgprB4 may provide genetic access to these elusive neurons in mice.",
author = "Qin Liu and Sophia Vrontou and Rice, {Frank L.} and Zylka, {Mark J.} and Xinzhong Dong and Anderson, {David J.}",
note = "Funding Information: We thank S. Pease for mouse assistance and J. Edens for electron microscopy. This work was supported by Alfred P. Sloan Neuroscience and Whitehall Foundation grants (X.D. and M.J.Z.), a Blaustein Pain research fund award (XD) and a European Molecular Biology Organization fellowship (S.V.). D.J.A. is an Investigator of the Howard Hughes Medical Institute. Copyright: Copyright 2009 Elsevier B.V., All rights reserved.",
year = "2007",
month = aug,
doi = "10.1038/nn1937",
language = "English (US)",
volume = "10",
pages = "946--948",
journal = "Nature neuroscience",
issn = "1097-6256",
publisher = "Nature Publishing Group",
number = "8",
}