Molecular-genetic imaging of cancer

Il Minn, Mitchell E. Menezes, Siddik Sarkar, Keerthi Yarlagadda, Swadesh K. Das, Luni Emdad, Devanand Sarkar, Paul B. Fisher, Martin Gilbert Pomper

Research output: Contribution to journalArticle

Abstract

Molecular-genetic imaging of cancer using nonviral delivery systems has great potential for clinical application as a safe, efficient, noninvasive tool for visualization of various cellular processes including detection of cancer, and its attendant metastases. In recent years, significant effort has been expended in overcoming technical hurdles to enable clinical adoption of molecular-genetic imaging. This chapter will provide an introduction to the components of molecular-genetic imaging and recent advances on each component leading to safe, efficient clinical applications for detecting cancer. Combination with therapy, namely, generating molecular-genetic theranostic constructs, will provide further impetus for clinical translation of this promising technology.

Original languageEnglish (US)
Pages (from-to)131-169
Number of pages39
JournalAdvances in Cancer Research
Volume124
DOIs
StatePublished - 2014

Fingerprint

Molecular Imaging
Molecular Biology
Neoplasms
Neoplasm Metastasis
Technology
Therapeutics

Keywords

  • Bioluminescence
  • Metastasis
  • Molecular imaging
  • PET
  • Promoter

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Minn, I., Menezes, M. E., Sarkar, S., Yarlagadda, K., Das, S. K., Emdad, L., ... Pomper, M. G. (2014). Molecular-genetic imaging of cancer. Advances in Cancer Research, 124, 131-169. https://doi.org/10.1016/B978-0-12-411638-2.00004-5

Molecular-genetic imaging of cancer. / Minn, Il; Menezes, Mitchell E.; Sarkar, Siddik; Yarlagadda, Keerthi; Das, Swadesh K.; Emdad, Luni; Sarkar, Devanand; Fisher, Paul B.; Pomper, Martin Gilbert.

In: Advances in Cancer Research, Vol. 124, 2014, p. 131-169.

Research output: Contribution to journalArticle

Minn, I, Menezes, ME, Sarkar, S, Yarlagadda, K, Das, SK, Emdad, L, Sarkar, D, Fisher, PB & Pomper, MG 2014, 'Molecular-genetic imaging of cancer', Advances in Cancer Research, vol. 124, pp. 131-169. https://doi.org/10.1016/B978-0-12-411638-2.00004-5
Minn I, Menezes ME, Sarkar S, Yarlagadda K, Das SK, Emdad L et al. Molecular-genetic imaging of cancer. Advances in Cancer Research. 2014;124:131-169. https://doi.org/10.1016/B978-0-12-411638-2.00004-5
Minn, Il ; Menezes, Mitchell E. ; Sarkar, Siddik ; Yarlagadda, Keerthi ; Das, Swadesh K. ; Emdad, Luni ; Sarkar, Devanand ; Fisher, Paul B. ; Pomper, Martin Gilbert. / Molecular-genetic imaging of cancer. In: Advances in Cancer Research. 2014 ; Vol. 124. pp. 131-169.
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