Abstract
Bacterial vaginosis (BV) is the most common cause of vaginal discharge in reproductive-age women. BV has been associated with poor reproductive outcomes such as preterm delivery, the acquisition of sexually transmitted infections, including HIV, and pelvic inflammatory disease. BV represents the acquisition of a diverse community of anaerobic and facultative bacteria and a reduction in lactobacilli. It can be diagnosed using several tests ranging from clinical indicators, point-of-care tests, and molecular assays. Molecular technologies are objective, are able to detect fastidious bacteria, enable quantitation, and are ideal for self-collected vaginal swabs. This paper reviews the currently available BV diagnostic tests in the United States.
| Original language | English (US) |
|---|---|
| Article number | e00342 |
| Journal | Journal of Clinical Microbiology |
| Volume | 56 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 1 2018 |
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Keywords
- bacterial vaginosis
- Real-time PCR
- Vaginal flora
ASJC Scopus subject areas
- Microbiology (medical)
Cite this
Molecular diagnosis of bacterial vaginosis : An update. / Coleman Fennell, Jenell S.; Gaydos, Charlotte A.
In: Journal of Clinical Microbiology, Vol. 56, No. 9, e00342, 01.09.2018.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Molecular diagnosis of bacterial vaginosis
T2 - An update
AU - Coleman Fennell, Jenell S.
AU - Gaydos, Charlotte A
PY - 2018/9/1
Y1 - 2018/9/1
N2 - Bacterial vaginosis (BV) is the most common cause of vaginal discharge in reproductive-age women. BV has been associated with poor reproductive outcomes such as preterm delivery, the acquisition of sexually transmitted infections, including HIV, and pelvic inflammatory disease. BV represents the acquisition of a diverse community of anaerobic and facultative bacteria and a reduction in lactobacilli. It can be diagnosed using several tests ranging from clinical indicators, point-of-care tests, and molecular assays. Molecular technologies are objective, are able to detect fastidious bacteria, enable quantitation, and are ideal for self-collected vaginal swabs. This paper reviews the currently available BV diagnostic tests in the United States.
AB - Bacterial vaginosis (BV) is the most common cause of vaginal discharge in reproductive-age women. BV has been associated with poor reproductive outcomes such as preterm delivery, the acquisition of sexually transmitted infections, including HIV, and pelvic inflammatory disease. BV represents the acquisition of a diverse community of anaerobic and facultative bacteria and a reduction in lactobacilli. It can be diagnosed using several tests ranging from clinical indicators, point-of-care tests, and molecular assays. Molecular technologies are objective, are able to detect fastidious bacteria, enable quantitation, and are ideal for self-collected vaginal swabs. This paper reviews the currently available BV diagnostic tests in the United States.
KW - bacterial vaginosis
KW - Real-time PCR
KW - Vaginal flora
UR - http://www.scopus.com/inward/record.url?scp=85052515328&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85052515328&partnerID=8YFLogxK
U2 - 10.1128/JCM.00342-1
DO - 10.1128/JCM.00342-1
M3 - Review article
C2 - 29769280
AN - SCOPUS:85052515328
VL - 56
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
SN - 0095-1137
IS - 9
M1 - e00342
ER -