Molecular cloning and analysis of cDNA encoding the murine c-yes tyrosine protein kinase

S. Klages, D. Adam, E. Eiseman, J. Fargnoli, S. M. Dymecki, S. V. Desiderio, J. B. Bolen

Research output: Contribution to journalArticle

Abstract

The cellular yes (c-yes) gene is a member of the class of proto-oncogenes that encode non-receptor tyrosine protein kinases. In this report we describe the isolation of cDNAs that encode the murine c-yes gene product and analysis of the nucleotide sequence of the murine c-yes cDNA clones. The reading frame encodes a protein of 541 amino acids with a calculated molecular mass of 60.63 kDa that is reactive with anti-Yes antisera and possesses protein kinase activity.

Original languageEnglish (US)
Pages (from-to)713-719
Number of pages7
JournalOncogene
Volume8
Issue number3
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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    Klages, S., Adam, D., Eiseman, E., Fargnoli, J., Dymecki, S. M., Desiderio, S. V., & Bolen, J. B. (1993). Molecular cloning and analysis of cDNA encoding the murine c-yes tyrosine protein kinase. Oncogene, 8(3), 713-719.