Molecular characterization of the drosophila trp locus: A putative integral membrane protein required for phototransduction

Craig Montell, Gerald M. Rubin

Research output: Contribution to journalArticlepeer-review

Abstract

Recent studies suggest that the fly uses the inositol lipid signaling system for visual excitation and that the Drosophila transient receptor potential (trp) mutation disrupts this process subsequent to the production of IP3. In this paper, we show that trp encodes a novel 1275 amino acid protein with eight putative transmembrane segments. Immunolocalization indicates that the trp protein is expressed predominantly in the rhabdomeric membranes of the photoreceptor cells.

Original languageEnglish (US)
Pages (from-to)1313-1323
Number of pages11
JournalNeuron
Volume2
Issue number4
DOIs
StatePublished - 1989
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

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