Molecular biology of nociceptors

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter begins with a functional classification of primary nociceptive neurons. It then presents current understanding of the molecules that allow nociceptors to detect noxious chemical, thermal, and mechanical stimuli. It describes the molecular processes by which this information is converted into action potentials and transmitted to the spinal cord. Finally, the chapter briefly describes the effects of an inflammatory insult on nociceptor function. For the sake of simplicity, it focuses primarily upon events related to cutaneous nociception.

Original languageEnglish (US)
Title of host publicationThe Neurobiology of Pain
Subtitle of host publication(Molecular and Cellular Neurobiology)
PublisherOxford University Press
ISBN (Electronic)9780191723650
ISBN (Print)9780198515616
DOIs
StatePublished - Jan 1 2010

Keywords

  • Cutaneous nociception
  • Inflammation
  • Molecular mechanisms
  • Nociceptive neurons
  • Nociceptors

ASJC Scopus subject areas

  • Neuroscience(all)

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