Molecular and functional imaging of cancer.

Research output: Contribution to journalArticle

Abstract

Because of the remarkable ability of cancer cells to adapt and survive, finding effective treatments against cancer depends upon identifying and attacking targets and pathways critically important for the cancer cell. The tumor physiological microenvironment, interactions between cancer cells and stromal cells such as endothelial cells, fibroblasts and macrophages, the extracellular matrix, and a multitude of secreted factors and cytokines influence progression, aggressiveness and response of the disease to treatment. Multi-modality and multi-parametric molecular and functional imaging provide unprecedented opportunities for understanding cancer. Some of our recent advances in molecular and functional imaging of cancer are discussed.

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Molecular Imaging
Cells
Imaging techniques
Neoplasms
Oncology
Macrophages
Endothelial cells
Fibroblasts
Tumors
Tumor Microenvironment
Stromal Cells
Extracellular Matrix
Endothelial Cells
Cytokines

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

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title = "Molecular and functional imaging of cancer.",
abstract = "Because of the remarkable ability of cancer cells to adapt and survive, finding effective treatments against cancer depends upon identifying and attacking targets and pathways critically important for the cancer cell. The tumor physiological microenvironment, interactions between cancer cells and stromal cells such as endothelial cells, fibroblasts and macrophages, the extracellular matrix, and a multitude of secreted factors and cytokines influence progression, aggressiveness and response of the disease to treatment. Multi-modality and multi-parametric molecular and functional imaging provide unprecedented opportunities for understanding cancer. Some of our recent advances in molecular and functional imaging of cancer are discussed.",
author = "Bhujwalla, {Zaver M.}",
year = "2009",
language = "English (US)",
pages = "47--49",
journal = "Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference",
issn = "1557-170X",
publisher = "Institute of Electrical and Electronics Engineers Inc.",

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AB - Because of the remarkable ability of cancer cells to adapt and survive, finding effective treatments against cancer depends upon identifying and attacking targets and pathways critically important for the cancer cell. The tumor physiological microenvironment, interactions between cancer cells and stromal cells such as endothelial cells, fibroblasts and macrophages, the extracellular matrix, and a multitude of secreted factors and cytokines influence progression, aggressiveness and response of the disease to treatment. Multi-modality and multi-parametric molecular and functional imaging provide unprecedented opportunities for understanding cancer. Some of our recent advances in molecular and functional imaging of cancer are discussed.

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