Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic acid

Maryjo Lechowicz, Dirk P. Dittmer, Jeannette Y. Lee, Susan E. Krown, William Wachsman, David Aboulafia, Bruce J. Dezube, Lee Ratner, Jonathan Said, Richard F. Ambinder

Research output: Contribution to journalArticle

Abstract

The AIDS Malignancy Consortium undertook a pilot trial of valproic acid among patients with AIDS-associated Kaposi sarcoma (KS). Treatment was associated with low toxicity, but the KS clinical response and KS herpesvirus lytic induction rates were not sufficiently high to meet predefined criteria for efficacy.

Original languageEnglish (US)
Pages (from-to)1946-1949
Number of pages4
JournalClinical Infectious Diseases
Volume49
Issue number12
DOIs
StatePublished - Dec 1 2009

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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    Lechowicz, M., Dittmer, D. P., Lee, J. Y., Krown, S. E., Wachsman, W., Aboulafia, D., Dezube, B. J., Ratner, L., Said, J., & Ambinder, R. F. (2009). Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic acid. Clinical Infectious Diseases, 49(12), 1946-1949. https://doi.org/10.1086/648447