Modified Alderman-Grant resonator with high-power stability for proton electron double resonance imaging

Sergey Petryakov, Alexandre Samouilov, Michael Roytenberg, Haihong Li, Jay L. Zweier

Research output: Contribution to journalArticle

Abstract

Proton-electron double resonance imaging (PEDRI) requires a dual EPR/NMR resonator. In order to saturate electron spins, long high-power RF EPR pulses are needed. Dissipated power causes resonator and sample heating, resulting in instability of the resonator frequency and coupling, which in turn causes a reduction in sensitivity. To overcome this problem, we designed, built, and tested a modified Alderman-Grant (MAG) resonator for in vivo and in vitro applications. We improved the temperature stability by using fused quartz in critical structural components of the resonator and employing a design that minimized moving parts. All of the components of the resonator and matching circuit, including coupling capacitors, were rigidly positioned on the surface of the quartz tube. Electrical coupling circuitry between the feeding cable and resonator was employed to provide independent coupling and tuning adjustments, which improved the ease and speed of operation. The equivalent schematic of the matching circuit is presented along with calculations of critical parameters. The resonator exhibits no frequency shift with 20 W of continuous power irradiation, and can handle intermittent power of 60 W for up to 3 min without detuning, enabling stable and reliable data acquisition for PEDRI of biological samples.

Original languageEnglish (US)
Pages (from-to)654-659
Number of pages6
JournalMagnetic Resonance in Medicine
Volume56
Issue number3
DOIs
StatePublished - Sep 2006
Externally publishedYes

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Keywords

  • Electron paramagnetic resonance
  • Free radicals
  • MRI
  • Overhauser effect
  • PEDRI
  • Radical metabolism

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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