Modifications of B, I, i, and Lewis antigens in a patient with DiGuglielmo's erythroleukemia

J. Kolins, J. W. Allgood, D. C. Burghardt, H. G. Klein, M. H. McGinniss

Research output: Contribution to journalArticle

Abstract

Loss of red blood cell antigens has been documented in patients with acute myelocytic leukemia and includes loss of A, B and H antigens in the ABO system as well as antigens of the Rh, MNSsU, Lewis and Ii systems. The following case represents partial loss of the B, I and Lewis(b) antigens in a patient with erythroleukemia. Also, the loss of the I antigen was associated with a concomitant increase in i antigen, a known but rare finding. These changes within the ABO, Ii, and Lewis systems do not appear to be coincidental, as these blood group systems share a common biochemical backbone.

Original languageEnglish (US)
Pages (from-to)574-577
Number of pages4
JournalTransfusion
Volume20
Issue number5
StatePublished - 1980
Externally publishedYes

ASJC Scopus subject areas

  • Hematology
  • Immunology

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    Kolins, J., Allgood, J. W., Burghardt, D. C., Klein, H. G., & McGinniss, M. H. (1980). Modifications of B, I, i, and Lewis antigens in a patient with DiGuglielmo's erythroleukemia. Transfusion, 20(5), 574-577.