Modeling the economic net benefit of a potential vaccination program against ocular infection with Chlamydia trachomatis

Kevin D. Frick, M. Arantxa Colchero, Deborah Dean

Research output: Contribution to journalArticle

Abstract

Trachoma is an ocular infection caused by Chlamydia trachomatis that carries a huge public health burden as a leading cause of preventable blindness globally. We developed a model of the economic benefits of a potential vaccine. Factors that impact the efficacy of a vaccination program (such as the sensitivity and specificity of algorithms to identify high-risk individuals), and personal and environmental risk factors for trachoma affect the maximum vaccination and screening costs at which a vaccination program can achieve a positive net benefit. This model is useful for planning vaccine programs in areas with varying trachoma risk factors and endemicity.

Original languageEnglish (US)
Pages (from-to)689-696
Number of pages8
JournalVaccine
Volume22
Issue number5-6
DOIs
StatePublished - Jan 26 2004

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Keywords

  • Chlamydia trachomatis
  • Cost-benefit analysis
  • Ocular infection
  • Vaccine

ASJC Scopus subject areas

  • Molecular Medicine
  • Immunology and Microbiology(all)
  • veterinary(all)
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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