When stimulated by chemoattractants, eukaryotic cells respond through a combination of temporal and spatial dynamics. These responses come about because of the interaction of a large number of signaling components. The complexity of these systems makes it hard to understand without a means of systematically generating and testing hypotheses. Computer simulations have proved to be useful in testing conceptual models. Here we outline the steps required to develop these models.
|Original language||English (US)|
|Number of pages||17|
|Journal||Methods in molecular biology (Clifton, N.J.)|
|State||Published - 2009|
ASJC Scopus subject areas
- Molecular Biology