Modeling spatial and temporal dynamics of chemotactic networks.

Research output: Contribution to journalArticle

Abstract

When stimulated by chemoattractants, eukaryotic cells respond through a combination of temporal and spatial dynamics. These responses come about because of the interaction of a large number of signaling components. The complexity of these systems makes it hard to understand without a means of systematically generating and testing hypotheses. Computer simulations have proved to be useful in testing conceptual models. Here we outline the steps required to develop these models.

Original languageEnglish (US)
Pages (from-to)489-505
Number of pages17
JournalMethods in molecular biology (Clifton, N.J.)
Volume571
StatePublished - 2009

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ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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