Abstract
When stimulated by chemoattractants, eukaryotic cells respond through a combination of temporal and spatial dynamics. These responses come about because of the interaction of a large number of signaling components. The complexity of these systems makes it hard to understand without a means of systematically generating and testing hypotheses. Computer simulations have proved to be useful in testing conceptual models. Here we outline the steps required to develop these models.
Original language | English (US) |
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Pages (from-to) | 489-505 |
Number of pages | 17 |
Journal | Methods in molecular biology (Clifton, N.J.) |
Volume | 571 |
DOIs | |
State | Published - 2009 |
ASJC Scopus subject areas
- Molecular Biology
- Genetics