Modeling respiratory mechanics in the MCAT and spline-based MCAT phantoms

W. P. Segars, D. S. Lalush, B. M.W. Tsui

Research output: Contribution to journalConference articlepeer-review


Respiratory motion can cause artifacts in myocardial SPECT and computed tomography (CT). We incorporate models of respiratory mechanics into the current 4D MCAT and into the next generation spline-based MCAT phantoms. In order to simulate respiratory motion in the current MCAT phantom, the geometric solids for the diaphragm, heart, ribs, and lungs were altered through manipulation of parameters defining them. Affine transformations were applied to the control points defining the same respiratory structures in the spline-based MCAT phantom to simulate respiratory motion. The Non-Uniform Rational B-Spline (NURBS) surfaces for the lungs and body outline were constructed in such a way as to be linked to the surrounding ribs. Expansion and contraction of the thoracic cage then coincided with expansion and contraction of the lungs and body. The changes both phantoms underwent were spline-interpolated over time to create time continuous 4D respiratory models. We then used the geometry-based and spline-based MCAT phantoms in an initial simulation study of the effects of respiratory motion on myocardial SPECT. The simulated reconstructed images demonstrated distinct artifacts in the inferior region of the myocardium. We conclude that both respiratory models can be effective tools for researching effects of respiratory motion.

Original languageEnglish (US)
Pages (from-to)89-97
Number of pages9
JournalIEEE Transactions on Nuclear Science
Issue number1 I
StatePublished - Feb 2001
Externally publishedYes
Event1999 Medical Imaging Conference (MIC) - Seattle, WA, United States
Duration: Oct 24 1999Oct 30 1999

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Nuclear Energy and Engineering
  • Electrical and Electronic Engineering


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