Modeling in vivo pharmacokinetics and pharmacodynamics of moxifloxacin therapy for Mycobacterium tuberculosis infection by using a novel cartridge system

Amy Sarah Ginsburg; Jin Lee; Samuel C. Woolwine; Jacques H. Grosset; Fayez M. Hamzeh; William R. Bishai

doi:10.1128/AAC.49.2.853-856.2005

Modeling in vivo pharmacokinetics and pharmacodynamics of moxifloxacin therapy for Mycobacterium tuberculosis infection by using a novel cartridge system

Amy Sarah Ginsburg, Jin Lee, Samuel C. Woolwine, Jacques H. Grosset, Fayez M. Hamzeh, William R. Bishai

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

To study the efficacy of moxifloxacin treatment for tuberculosis, we utilized a novel cartridge system to simulate in vivo pharmacokinetics. We found this system to be a robust method for modeling in vivo pharmacokinetics and present data supporting the utility of intermittent moxifloxacin treatment as a component of antituberculosis chemotherapy.

Original language	English (US)
Pages (from-to)	853-856
Number of pages	4
Journal	Antimicrobial agents and chemotherapy
Volume	49
Issue number	2
DOIs	https://doi.org/10.1128/AAC.49.2.853-856.2005
State	Published - Feb 2005

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.49.2.853-856.2005

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abstract = "To study the efficacy of moxifloxacin treatment for tuberculosis, we utilized a novel cartridge system to simulate in vivo pharmacokinetics. We found this system to be a robust method for modeling in vivo pharmacokinetics and present data supporting the utility of intermittent moxifloxacin treatment as a component of antituberculosis chemotherapy.",

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AU - Hamzeh, Fayez M.

AU - Bishai, William R.

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Modeling in vivo pharmacokinetics and pharmacodynamics of moxifloxacin therapy for Mycobacterium tuberculosis infection by using a novel cartridge system

Abstract

ASJC Scopus subject areas

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