A model which relates the time-dependent coronary blood flow distribution to the intramyocardial pressure has been developed. The left ventricular (LV) mechanical parameters were calculated on the basis of a recent model which uses spheroidal nested shell geometry, fiber angle distribution, sarcomere dynamics, and transmural electrical activation. The instantaneous coronary flow at any distance from the endocardium is defined by the waterfall concept, which relates the instantaneous flow to the differences between the coronary pressure and the zero flow pressure divided by the coronary resistance. This is further linked with the local oxygen demand determined by the local loading conditions. The calculated results described here are consistent with various experimental data, providing insight into the mechanisms of coronary flow.
|Original language||English (US)|
|Title of host publication||Computers in Cardiology|
|Editors||Kenneth L. Ripley|
|Number of pages||4|
|State||Published - 1984|
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine