MODEL FOR THE INTERACTION BETWEEN THE MECHANICS AND THE CORONARY PERFUSION OF THE LEFT VENTRICLE BASED ON THE TRANSMURAL OXYGEN DEMAND.

Rafael Beyer, Samuel Sideman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A model which relates the time-dependent coronary blood flow distribution to the intramyocardial pressure has been developed. The left ventricular (LV) mechanical parameters were calculated on the basis of a recent model which uses spheroidal nested shell geometry, fiber angle distribution, sarcomere dynamics, and transmural electrical activation. The instantaneous coronary flow at any distance from the endocardium is defined by the waterfall concept, which relates the instantaneous flow to the differences between the coronary pressure and the zero flow pressure divided by the coronary resistance. This is further linked with the local oxygen demand determined by the local loading conditions. The calculated results described here are consistent with various experimental data, providing insight into the mechanisms of coronary flow.

Original languageEnglish (US)
Title of host publicationComputers in Cardiology
EditorsKenneth L. Ripley
PublisherIEEE
Pages203-206
Number of pages4
ISBN (Print)0818605472
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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  • Cite this

    Beyer, R., & Sideman, S. (1984). MODEL FOR THE INTERACTION BETWEEN THE MECHANICS AND THE CORONARY PERFUSION OF THE LEFT VENTRICLE BASED ON THE TRANSMURAL OXYGEN DEMAND. In K. L. Ripley (Ed.), Computers in Cardiology (pp. 203-206). IEEE.