Modality-specific alterations in the perception of emotional stimuli in Bipolar Disorder compared to Healthy Controls and Major Depressive Disorder

Aaron C. Vederman, Sara L. Weisenbach, Lisa J. Rapport, Hadia M. Leon, Brennan D. Haase, Lindsay M. Franti, Michael Paul Schallmo, Erika F H Saunders, Masoud M. Kamali, Jon Kar Zubieta, Scott A. Langenecker, Melvin G. McInnis

Research output: Contribution to journalArticle

Abstract

Objectives: Affect identification accuracy paradigms have increasingly been utilized to understand psychiatric illness including Bipolar Disorder (BD) and Major Depressive Disorder (MDD). This investigation focused on perceptual accuracy in affect identification in both visual and auditory domains among patients with BD, relative to Healthy Controls (HC) and patients with MDD. Demographic and clinical variables, in addition to medications were also investigated. Method: The visual Facial Emotion Perception Test (FEPT) and auditory Emotional Perception Test (EPT) were administered to adults with BD (n= 119) and MDD (n= 78) as well as HC (n= 66). Results: Performance on the FEPT was significantly stronger than on the EPT irrespective of group. Performance on the EPT did not significantly differentiate the groups. On the FEPT, BD samples had the greatest difficulty relative to HC in identification of sad and fearful faces. BD participants also had greater difficulty identifying sad faces relative to MDD participants though not after controlling for severity of illness factors. For the BD (but not MDD) sample several clinical variables were also correlated with FEPT performance. Conclusions: The findings suggest that disruptions in identification of negative emotions such as sadness and fear may be a characteristic trait of BD. However, this effect may be moderated by greater illness severity found in our BD sample.

Original languageEnglish (US)
Pages (from-to)1027-1034
Number of pages8
JournalCortex
Volume48
Issue number8
DOIs
StatePublished - Sep 2012
Externally publishedYes

Fingerprint

Major Depressive Disorder
Bipolar Disorder
Emotions
Auditory Perception
Modality
Alteration
Emotion
Stimulus
Fear
Psychiatry
Demography

Keywords

  • Affect perception
  • Bipolar Disorder
  • Major Depressive Disorder

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Arts and Humanities (miscellaneous)
  • Developmental and Educational Psychology

Cite this

Vederman, A. C., Weisenbach, S. L., Rapport, L. J., Leon, H. M., Haase, B. D., Franti, L. M., ... McInnis, M. G. (2012). Modality-specific alterations in the perception of emotional stimuli in Bipolar Disorder compared to Healthy Controls and Major Depressive Disorder. Cortex, 48(8), 1027-1034. https://doi.org/10.1016/j.cortex.2011.03.017

Modality-specific alterations in the perception of emotional stimuli in Bipolar Disorder compared to Healthy Controls and Major Depressive Disorder. / Vederman, Aaron C.; Weisenbach, Sara L.; Rapport, Lisa J.; Leon, Hadia M.; Haase, Brennan D.; Franti, Lindsay M.; Schallmo, Michael Paul; Saunders, Erika F H; Kamali, Masoud M.; Zubieta, Jon Kar; Langenecker, Scott A.; McInnis, Melvin G.

In: Cortex, Vol. 48, No. 8, 09.2012, p. 1027-1034.

Research output: Contribution to journalArticle

Vederman, AC, Weisenbach, SL, Rapport, LJ, Leon, HM, Haase, BD, Franti, LM, Schallmo, MP, Saunders, EFH, Kamali, MM, Zubieta, JK, Langenecker, SA & McInnis, MG 2012, 'Modality-specific alterations in the perception of emotional stimuli in Bipolar Disorder compared to Healthy Controls and Major Depressive Disorder', Cortex, vol. 48, no. 8, pp. 1027-1034. https://doi.org/10.1016/j.cortex.2011.03.017
Vederman, Aaron C. ; Weisenbach, Sara L. ; Rapport, Lisa J. ; Leon, Hadia M. ; Haase, Brennan D. ; Franti, Lindsay M. ; Schallmo, Michael Paul ; Saunders, Erika F H ; Kamali, Masoud M. ; Zubieta, Jon Kar ; Langenecker, Scott A. ; McInnis, Melvin G. / Modality-specific alterations in the perception of emotional stimuli in Bipolar Disorder compared to Healthy Controls and Major Depressive Disorder. In: Cortex. 2012 ; Vol. 48, No. 8. pp. 1027-1034.
@article{fa443290af0e4585a4e062392e8fc9ba,
title = "Modality-specific alterations in the perception of emotional stimuli in Bipolar Disorder compared to Healthy Controls and Major Depressive Disorder",
abstract = "Objectives: Affect identification accuracy paradigms have increasingly been utilized to understand psychiatric illness including Bipolar Disorder (BD) and Major Depressive Disorder (MDD). This investigation focused on perceptual accuracy in affect identification in both visual and auditory domains among patients with BD, relative to Healthy Controls (HC) and patients with MDD. Demographic and clinical variables, in addition to medications were also investigated. Method: The visual Facial Emotion Perception Test (FEPT) and auditory Emotional Perception Test (EPT) were administered to adults with BD (n= 119) and MDD (n= 78) as well as HC (n= 66). Results: Performance on the FEPT was significantly stronger than on the EPT irrespective of group. Performance on the EPT did not significantly differentiate the groups. On the FEPT, BD samples had the greatest difficulty relative to HC in identification of sad and fearful faces. BD participants also had greater difficulty identifying sad faces relative to MDD participants though not after controlling for severity of illness factors. For the BD (but not MDD) sample several clinical variables were also correlated with FEPT performance. Conclusions: The findings suggest that disruptions in identification of negative emotions such as sadness and fear may be a characteristic trait of BD. However, this effect may be moderated by greater illness severity found in our BD sample.",
keywords = "Affect perception, Bipolar Disorder, Major Depressive Disorder",
author = "Vederman, {Aaron C.} and Weisenbach, {Sara L.} and Rapport, {Lisa J.} and Leon, {Hadia M.} and Haase, {Brennan D.} and Franti, {Lindsay M.} and Schallmo, {Michael Paul} and Saunders, {Erika F H} and Kamali, {Masoud M.} and Zubieta, {Jon Kar} and Langenecker, {Scott A.} and McInnis, {Melvin G.}",
year = "2012",
month = "9",
doi = "10.1016/j.cortex.2011.03.017",
language = "English (US)",
volume = "48",
pages = "1027--1034",
journal = "Cortex",
issn = "0010-9452",
publisher = "Masson SpA",
number = "8",

}

TY - JOUR

T1 - Modality-specific alterations in the perception of emotional stimuli in Bipolar Disorder compared to Healthy Controls and Major Depressive Disorder

AU - Vederman, Aaron C.

AU - Weisenbach, Sara L.

AU - Rapport, Lisa J.

AU - Leon, Hadia M.

AU - Haase, Brennan D.

AU - Franti, Lindsay M.

AU - Schallmo, Michael Paul

AU - Saunders, Erika F H

AU - Kamali, Masoud M.

AU - Zubieta, Jon Kar

AU - Langenecker, Scott A.

AU - McInnis, Melvin G.

PY - 2012/9

Y1 - 2012/9

N2 - Objectives: Affect identification accuracy paradigms have increasingly been utilized to understand psychiatric illness including Bipolar Disorder (BD) and Major Depressive Disorder (MDD). This investigation focused on perceptual accuracy in affect identification in both visual and auditory domains among patients with BD, relative to Healthy Controls (HC) and patients with MDD. Demographic and clinical variables, in addition to medications were also investigated. Method: The visual Facial Emotion Perception Test (FEPT) and auditory Emotional Perception Test (EPT) were administered to adults with BD (n= 119) and MDD (n= 78) as well as HC (n= 66). Results: Performance on the FEPT was significantly stronger than on the EPT irrespective of group. Performance on the EPT did not significantly differentiate the groups. On the FEPT, BD samples had the greatest difficulty relative to HC in identification of sad and fearful faces. BD participants also had greater difficulty identifying sad faces relative to MDD participants though not after controlling for severity of illness factors. For the BD (but not MDD) sample several clinical variables were also correlated with FEPT performance. Conclusions: The findings suggest that disruptions in identification of negative emotions such as sadness and fear may be a characteristic trait of BD. However, this effect may be moderated by greater illness severity found in our BD sample.

AB - Objectives: Affect identification accuracy paradigms have increasingly been utilized to understand psychiatric illness including Bipolar Disorder (BD) and Major Depressive Disorder (MDD). This investigation focused on perceptual accuracy in affect identification in both visual and auditory domains among patients with BD, relative to Healthy Controls (HC) and patients with MDD. Demographic and clinical variables, in addition to medications were also investigated. Method: The visual Facial Emotion Perception Test (FEPT) and auditory Emotional Perception Test (EPT) were administered to adults with BD (n= 119) and MDD (n= 78) as well as HC (n= 66). Results: Performance on the FEPT was significantly stronger than on the EPT irrespective of group. Performance on the EPT did not significantly differentiate the groups. On the FEPT, BD samples had the greatest difficulty relative to HC in identification of sad and fearful faces. BD participants also had greater difficulty identifying sad faces relative to MDD participants though not after controlling for severity of illness factors. For the BD (but not MDD) sample several clinical variables were also correlated with FEPT performance. Conclusions: The findings suggest that disruptions in identification of negative emotions such as sadness and fear may be a characteristic trait of BD. However, this effect may be moderated by greater illness severity found in our BD sample.

KW - Affect perception

KW - Bipolar Disorder

KW - Major Depressive Disorder

UR - http://www.scopus.com/inward/record.url?scp=84863779464&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863779464&partnerID=8YFLogxK

U2 - 10.1016/j.cortex.2011.03.017

DO - 10.1016/j.cortex.2011.03.017

M3 - Article

VL - 48

SP - 1027

EP - 1034

JO - Cortex

JF - Cortex

SN - 0010-9452

IS - 8

ER -