Mobile elements and the human genome

Eline T. Luning Prak, Haig H. Kazazian

Research output: Contribution to journalReview article

Abstract

Genomic DNA is often thought of as the stable template of heredity, largely dormant and unchanging, apart from perhaps the occasional point mutation. But it has become increasingly clear that DNA is dynamic rather than static, being subjected to rearrangements, insertions and deletions. Much of this plasticity can be attributed to transposable elements and their genomic relatives.

Original languageEnglish (US)
Pages (from-to)134-144
Number of pages11
JournalNature Reviews Genetics
Volume1
Issue number2
DOIs
StatePublished - Nov 2000
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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