Mobile elements and the human genome

Eline T. Luning Prak, Haig H. Kazazian

Research output: Contribution to journalReview article

Abstract

Genomic DNA is often thought of as the stable template of heredity, largely dormant and unchanging, apart from perhaps the occasional point mutation. But it has become increasingly clear that DNA is dynamic rather than static, being subjected to rearrangements, insertions and deletions. Much of this plasticity can be attributed to transposable elements and their genomic relatives.

Original languageEnglish (US)
Pages (from-to)134-144
Number of pages11
JournalNature Reviews Genetics
Volume1
Issue number2
StatePublished - Nov 2000
Externally publishedYes

Fingerprint

Human Genome
genomics
Heredity
DNA Transposable Elements
genome
DNA
point mutation
Point Mutation
transposons
inheritance (genetics)

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Genetics
  • Genetics(clinical)

Cite this

Mobile elements and the human genome. / Luning Prak, Eline T.; Kazazian, Haig H.

In: Nature Reviews Genetics, Vol. 1, No. 2, 11.2000, p. 134-144.

Research output: Contribution to journalReview article

Luning Prak, ET & Kazazian, HH 2000, 'Mobile elements and the human genome', Nature Reviews Genetics, vol. 1, no. 2, pp. 134-144.
Luning Prak, Eline T. ; Kazazian, Haig H. / Mobile elements and the human genome. In: Nature Reviews Genetics. 2000 ; Vol. 1, No. 2. pp. 134-144.
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