Mobile elements and disease

Research output: Contribution to journalArticlepeer-review

Abstract

LTR-retrotransposons, non-LTR retrotransposons, and non-autonomous retrotransposons have caused disease frequently in mice, but infrequently in humans. Although many of these elements are defective, a number of mammalian non-LTR retrotransposons of the L1 type are capable of autonomous retrotransposition. The mechanism by which they retrotranspose and in turn aide the retrotransposition of non-autonomous elements is being elucidated.

Original languageEnglish (US)
Pages (from-to)343-350
Number of pages8
JournalCurrent Opinion in Genetics and Development
Volume8
Issue number3
DOIs
StatePublished - Jun 1998
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

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