Mn-salen catalysed benzylic C-H activation for the synthesis of aryl [18F]CF3-containing PET probes

L. Carroll, H. L. Evans, A. C. Spivey, E. O. Aboagye

Research output: Contribution to journalArticle


The development of a Mn-salen complex catalysed oxidative benzylic fluorination of non-activated C-H bonds using [18F]fluoride is described for installation of [18F]CHRF, [18F]CR2F and particularly [18F]CF3 containing groups in the presence of other functional groups.

Original languageEnglish (US)
Pages (from-to)8439-8441
Number of pages3
JournalChemical Communications
Issue number40
StatePublished - May 18 2015


ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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