MLVA genotyping of human Brucella isolates from Peru

Henk L. Smits, Benjamin Espinosa, Rosa Castillo, Eric Hall, Alfredo Guillen, Milagros Zevaleta, Robert H. Gilman, Paolo Melendez, Carlos Guerra, Angelika Draeger, Alessandro Broglia, Karsten Nöckler

Research output: Contribution to journalArticlepeer-review

Abstract

Recent human Brucella melitensis isolates from Peru were genotyped by multiple locus variable number repeat analysis. All 24 isolates originated from hospitalized patients living in the central part of Peru and consisted of six genomic groups comprising two to four isolates and nine unique genotypes. The isolates were most closely related to the two previously genotyped isolates from Mexico, with a maximum distance of 2 to 4. The Peruvian strains were clearly distinct from the East and West Mediterranean groups of B. melitensis genotypes, suggesting that they may constitute a unique Latin American cluster.

Original languageEnglish (US)
Pages (from-to)399-402
Number of pages4
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume103
Issue number4
DOIs
StatePublished - Apr 1 2009

Keywords

  • Brucella melitensis
  • Brucellosis
  • Genotyping
  • Latin America
  • Reinfection
  • Relapse

ASJC Scopus subject areas

  • Parasitology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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