MIRD pamphlet No. 24: Guidelines for quantitative 131I SPECT in dosimetry applications

Yuni K. Dewaraja, Michael Ljungberg, Alan J. Green, Pat B. Zanzonico, Eric C. Frey, Wesley E. Bolch, A. Bertrand Brill, Mark Dunphy, Darrell R. Fisher, Roger W. Howell, Ruby F. Meredith, George Sgouros, Barry W. Wessels

Research output: Contribution to journalArticle

Abstract

The reliability of radiation dose estimates in internal radionuclide therapy is directly related to the accuracy of activity estimates obtained at each imaging time point. The recently published MIRD pamphlet no. 23 provided a general overview of quantitative SPECT imaging for dosimetry. The present document is the first in a series of isotopespecific guidelines that will follow MIRD 23 and focuses on one of the most commonly used therapeutic radionuclides, 131I. The purpose of this document is to provide guidance on the development of protocols for quantitative 131I SPECT in radionuclide therapy applications that require regional (normal organs, lesions) and 3-dimensional dosimetry. COPYRIGHT

Original languageEnglish (US)
Pages (from-to)2182-2188
Number of pages7
JournalJournal of Nuclear Medicine
Volume54
Issue number12
DOIs
StatePublished - Dec 1 2013

Keywords

  • MIRD
  • Quantitative SPECT
  • SPECT/CT, dosimetry

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Dewaraja, Y. K., Ljungberg, M., Green, A. J., Zanzonico, P. B., Frey, E. C., Bolch, W. E., Brill, A. B., Dunphy, M., Fisher, D. R., Howell, R. W., Meredith, R. F., Sgouros, G., & Wessels, B. W. (2013). MIRD pamphlet No. 24: Guidelines for quantitative 131I SPECT in dosimetry applications. Journal of Nuclear Medicine, 54(12), 2182-2188. https://doi.org/10.2967/jnumed.113.122390