MIRD pamphlet No. 24: Guidelines for quantitative 131I SPECT in dosimetry applications

Yuni K. Dewaraja; Michael Ljungberg; Alan J. Green; Pat B. Zanzonico; Eric Frey; Wesley E. Bolch; A. Bertrand Brill; Mark Dunphy; Darrell R. Fisher; Roger W. Howell; Ruby F. Meredith; George Sgouros; Barry W. Wessels

doi:10.2967/jnumed.113.122390

MIRD pamphlet No. 24: Guidelines for quantitative ¹³¹I SPECT in dosimetry applications

Yuni K. Dewaraja, Michael Ljungberg, Alan J. Green, Pat B. Zanzonico, Eric Frey, Wesley E. Bolch, A. Bertrand Brill, Mark Dunphy, Darrell R. Fisher, Roger W. Howell, Ruby F. Meredith, George Sgouros, Barry W. Wessels

School of Medicine

Research output: Contribution to journal › Article › peer-review

63 Scopus citations

Abstract

The reliability of radiation dose estimates in internal radionuclide therapy is directly related to the accuracy of activity estimates obtained at each imaging time point. The recently published MIRD pamphlet no. 23 provided a general overview of quantitative SPECT imaging for dosimetry. The present document is the first in a series of isotopespecific guidelines that will follow MIRD 23 and focuses on one of the most commonly used therapeutic radionuclides, ¹³¹I. The purpose of this document is to provide guidance on the development of protocols for quantitative ¹³¹I SPECT in radionuclide therapy applications that require regional (normal organs, lesions) and 3-dimensional dosimetry. COPYRIGHT

Original language	English (US)
Pages (from-to)	2182-2188
Number of pages	7
Journal	Journal of Nuclear Medicine
Volume	54
Issue number	12
DOIs	https://doi.org/10.2967/jnumed.113.122390
State	Published - Dec 1 2013

Keywords

MIRD
Quantitative SPECT
SPECT/CT, dosimetry

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.2967/jnumed.113.122390

Cite this

Dewaraja, Y. K., Ljungberg, M., Green, A. J., Zanzonico, P. B., Frey, E., Bolch, W. E., Brill, A. B., Dunphy, M., Fisher, D. R., Howell, R. W., Meredith, R. F., Sgouros, G., & Wessels, B. W. (2013). MIRD pamphlet No. 24: Guidelines for quantitative ¹³¹I SPECT in dosimetry applications. Journal of Nuclear Medicine, 54(12), 2182-2188. https://doi.org/10.2967/jnumed.113.122390

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abstract = "The reliability of radiation dose estimates in internal radionuclide therapy is directly related to the accuracy of activity estimates obtained at each imaging time point. The recently published MIRD pamphlet no. 23 provided a general overview of quantitative SPECT imaging for dosimetry. The present document is the first in a series of isotopespecific guidelines that will follow MIRD 23 and focuses on one of the most commonly used therapeutic radionuclides, 131I. The purpose of this document is to provide guidance on the development of protocols for quantitative 131I SPECT in radionuclide therapy applications that require regional (normal organs, lesions) and 3-dimensional dosimetry. COPYRIGHT",

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AU - Frey, Eric

AU - Bolch, Wesley E.

AU - Brill, A. Bertrand

AU - Dunphy, Mark

AU - Fisher, Darrell R.

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