Minimally invasive intraventricular ultrasound: Design and instrumentation towards a miniaturized ultrasound-guided focused ultrasound probe

Micah Belzberg, Francisco Chavez, Kah Timothy Xiong, Kyle Morrison, Nao Gamo, Stephen Restaino, Rajiv Iyer, Mari Groves, Nitish Thakor, Henry Brem, Alan Cohen, Amir Manbachi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Neurosurgery typically requires craniectomy and meticulous dissection to achieve sufficient exposure for subsequent surgical intervention. This highly invasive process requires hours of operating time, long recovery periods and leaves patients with visible surgical scars. Non-invasive high-intensity focused ultrasound (HIFU) has shown some promise yet remains challenged by the attenuation of ultrasonic waves while passing through the skull. Consequently, the clinical impact of this technology remains limited, particularly in the treatment of neuro-oncology. In order to compensate for acoustic attenuation, excessive use of power for HIFU devices has been investigated, although it is undesirable from a regulatory and patient safety standpoint. Here, we report the design and development of a novel HIFU device prototype for neurologic lesion ablation. This device concept is envisioned to access the ventricular space via a minimally invasive ventriculostomy, allowing ultrasound to reach targets deep in the brain, while eliminating the need for high power to penetrate the skull.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2019
Subtitle of host publicationImage-Guided Procedures, Robotic Interventions, and Modeling
EditorsBaowei Fei, Cristian A. Linte
PublisherSPIE
ISBN (Electronic)9781510625495
DOIs
StatePublished - Jan 1 2019
EventMedical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling - San Diego, United States
Duration: Feb 17 2019Feb 19 2019

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10951
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling
CountryUnited States
CitySan Diego
Period2/17/192/19/19

Keywords

  • Focused Ultrasound
  • Instrumentation
  • Minimally Invasive Surgery
  • Neurosurgery
  • Oncology
  • Therapeutic Ultrasound
  • Ultrasound
  • Ventricles

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Belzberg, M., Chavez, F., Xiong, K. T., Morrison, K., Gamo, N., Restaino, S., Iyer, R., Groves, M., Thakor, N., Brem, H., Cohen, A., & Manbachi, A. (2019). Minimally invasive intraventricular ultrasound: Design and instrumentation towards a miniaturized ultrasound-guided focused ultrasound probe. In B. Fei, & C. A. Linte (Eds.), Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling [109512Y] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10951). SPIE. https://doi.org/10.1117/12.2513150