Miniature elastomeric valve design for safe direct current stimulator

Chaojun Cheng, Raviraj Thakur, Ankitha Rajagopalan Nair, Scott Sterrett, Gene Fridman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

For safety reasons, commercial neural implants use charge-balanced biphasic pulses to interact with target neurons using metal electrodes. Short biphasic pulses are used to avoid irreversible electrochemical reactions at the electrode-tissue interfaces. Biphasic pulses are effective at exciting neurons, but quite limited in inhibiting their activity. In contrast, direct current can both excite and inhibit neurons, however delivered to metal electrodes, it causes toxic electrochemical reactions. We recently introduced Safe Direct Current Stimulator (SDCS) technology, which can excite or inhibit neurons without violating the safety criteria. Instead of direct current, SDCS generates an ionic direct current (iDC) from a biphasic input signal using a network of fluidic channels and mechanical valves. A key enabler towards transforming SDCS concept from a benchtop design to an implantable neural prosthesis is the design of a miniature valve. In this work, we present poly-dimethylsiloxane (PDMS) based elastomeric valves, squeeze valve (SV) and plunger valve (PV) capable of being actuated using a shape memory alloy wire.

Original languageEnglish (US)
Title of host publication2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1-4
Number of pages4
ISBN (Electronic)9781509058037
DOIs
StatePublished - Mar 23 2018
Event2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Torino, Italy
Duration: Oct 19 2017Oct 21 2017

Publication series

Name2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings
Volume2018-January

Other

Other2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017
CountryItaly
CityTorino
Period10/19/1710/21/17

Keywords

  • PDMS
  • ionic direct current
  • microfluidic valve
  • neural inhibition
  • shape memory alloy

ASJC Scopus subject areas

  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Instrumentation

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