Abstract
Background Interventions that promote mindfulness consistently show salutary effects on cognition and emotional wellbeing in adults, and more recently, in children and adolescents. However, we lack understanding of the neurobiological mechanisms underlying mindfulness in youth that should allow for more judicious application of these interventions in clinical and educational settings. Methods Using multi-echo multi-band fMRI, we examined dynamic (i.e., time-varying) and conventional static resting-state connectivity between core neurocognitive networks (i.e., salience/emotion, default mode, central executive) in 42 children and adolescents (ages 6–17). Results We found that trait mindfulness in youth relates to dynamic but not static resting-state connectivity. Specifically, more mindful youth transitioned more between brain states over the course of the scan, spent overall less time in a certain connectivity state, and showed a state-specific reduction in connectivity between salience/emotion and central executive networks. The number of state transitions mediated the link between higher mindfulness and lower anxiety, providing new insights into potential neural mechanisms underlying benefits of mindfulness on psychological health in youth. Conclusions Our results provide new evidence that mindfulness in youth relates to functional neural dynamics and interactions between neurocognitive networks, over time.
| Language | English (US) |
|---|---|
| Pages | 211-218 |
| Number of pages | 8 |
| Journal | Behavioural Brain Research |
| Volume | 336 |
| DOIs | |
| State | Published - Jan 15 2018 |
| Externally published | Yes |
Fingerprint
Keywords
- Default mode network
- Independent components analysis
- Intrinsic connectivity
- Meditation
- Resting-state
- Salience network
ASJC Scopus subject areas
- Behavioral Neuroscience
Cite this
Mindfulness and dynamic functional neural connectivity in children and adolescents. / Marusak, Hilary A.; Elrahal, Farrah; Peters, Craig A.; Kundu, Prantik; Lombardo, Michael V.; Calhoun, Vince D.; Goldberg, Elimelech K.; Cohen, Cindy; Taub, Jeffrey W.; Rabinak, Christine A.
In: Behavioural Brain Research, Vol. 336, 15.01.2018, p. 211-218.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mindfulness and dynamic functional neural connectivity in children and adolescents
AU - Marusak,Hilary A.
AU - Elrahal,Farrah
AU - Peters,Craig A.
AU - Kundu,Prantik
AU - Lombardo,Michael V.
AU - Calhoun,Vince D.
AU - Goldberg,Elimelech K.
AU - Cohen,Cindy
AU - Taub,Jeffrey W.
AU - Rabinak,Christine A.
PY - 2018/1/15
Y1 - 2018/1/15
N2 - Background Interventions that promote mindfulness consistently show salutary effects on cognition and emotional wellbeing in adults, and more recently, in children and adolescents. However, we lack understanding of the neurobiological mechanisms underlying mindfulness in youth that should allow for more judicious application of these interventions in clinical and educational settings. Methods Using multi-echo multi-band fMRI, we examined dynamic (i.e., time-varying) and conventional static resting-state connectivity between core neurocognitive networks (i.e., salience/emotion, default mode, central executive) in 42 children and adolescents (ages 6–17). Results We found that trait mindfulness in youth relates to dynamic but not static resting-state connectivity. Specifically, more mindful youth transitioned more between brain states over the course of the scan, spent overall less time in a certain connectivity state, and showed a state-specific reduction in connectivity between salience/emotion and central executive networks. The number of state transitions mediated the link between higher mindfulness and lower anxiety, providing new insights into potential neural mechanisms underlying benefits of mindfulness on psychological health in youth. Conclusions Our results provide new evidence that mindfulness in youth relates to functional neural dynamics and interactions between neurocognitive networks, over time.
AB - Background Interventions that promote mindfulness consistently show salutary effects on cognition and emotional wellbeing in adults, and more recently, in children and adolescents. However, we lack understanding of the neurobiological mechanisms underlying mindfulness in youth that should allow for more judicious application of these interventions in clinical and educational settings. Methods Using multi-echo multi-band fMRI, we examined dynamic (i.e., time-varying) and conventional static resting-state connectivity between core neurocognitive networks (i.e., salience/emotion, default mode, central executive) in 42 children and adolescents (ages 6–17). Results We found that trait mindfulness in youth relates to dynamic but not static resting-state connectivity. Specifically, more mindful youth transitioned more between brain states over the course of the scan, spent overall less time in a certain connectivity state, and showed a state-specific reduction in connectivity between salience/emotion and central executive networks. The number of state transitions mediated the link between higher mindfulness and lower anxiety, providing new insights into potential neural mechanisms underlying benefits of mindfulness on psychological health in youth. Conclusions Our results provide new evidence that mindfulness in youth relates to functional neural dynamics and interactions between neurocognitive networks, over time.
KW - Default mode network
KW - Independent components analysis
KW - Intrinsic connectivity
KW - Meditation
KW - Resting-state
KW - Salience network
UR - http://www.scopus.com/inward/record.url?scp=85028974319&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85028974319&partnerID=8YFLogxK
U2 - 10.1016/j.bbr.2017.09.010
DO - 10.1016/j.bbr.2017.09.010
M3 - Article
VL - 336
SP - 211
EP - 218
JO - Behavioural Brain Research
T2 - Behavioural Brain Research
JF - Behavioural Brain Research
SN - 0166-4328
ER -