Midline abnormalities and psychopathology: how reliable is the midsagittal magnetic resonance "window" into the brain?

Richard Coppola, Michael Myslobodsky, Daniel R. Weinberger

Research output: Contribution to journalArticlepeer-review

Abstract

The argument is made that mensuration of midsagittal magnetic resonance (MR) images is plagued with methodological errors due to confusion of the midsagittal MR image and the mesial brain surface. Several examples are given to demonstrate the effects of slice thickness and orientation on the size and shape of mesial structures. The benefits of examining contiguous slices and the necessity of consulting coronal and transaxial cuts in mensuration efforts of midsagittal cuts are emphasized.

Original languageEnglish (US)
Pages (from-to)33-42
Number of pages10
JournalPsychiatry Research: Neuroimaging
Volume61
Issue number1
DOIs
StatePublished - May 31 1995
Externally publishedYes

Keywords

  • Corpus callosum
  • Frontal lobe atrophy
  • Magnetic resonance imaging, midsagittal cut
  • Vermal atrophy

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Psychiatry and Mental health

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