Microscopic hemodynamics and hemorheology with the immersed-boundary lattice-boltzmann method

J. Zhang, P. C. Johnson, A. S. Popel

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Red blood cells are the most important constituents of blood due to their physiological importance and hemodynamic significance. To study the motion of red blood cells in the microcirculation, an immersed-boundary/lattice- Boltzmann method is developed integrating fluid flow and membrane mechanics, and also accounting for cell aggregation. A detailed description of the computational modules is provided, including a lattice-Boltzmann method for fluid mechanics, an immersed-boundary method for fluid-membrane interaction, an explicit fluid property updating algorithm, and a Morse potential for modeling intercellular aggregation. Simulations are presented for several flow configurations to demonstrate the potentiality and usefulness of the computational approach.

Original languageEnglish (US)
Title of host publicationComputational Hydrodynamics of Capsules and Biological Cells
PublisherCRC Press
Pages113-148
Number of pages36
ISBN (Electronic)9781439820063
ISBN (Print)9781439820056
DOIs
StatePublished - Jan 1 2010

ASJC Scopus subject areas

  • Mathematics(all)
  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Physics and Astronomy(all)

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