MicroRNAs in Parkinson's disease

Research output: Contribution to journalArticle

Abstract

MicroRNAs are small non-protein coding RNAs that regulate gene expression through post-transcriptional repression. Recent studies demonstrated the importance of microRNAs in the nervous system development, function and disease. Parkinson's disease is the second most prevalent neurodegenerative disease with only symptomatic treatment available. Recent success in using small RNAs as therapeutic targets hold a substantial promise for the Parkinson's disease field. Here we review recent work linking the microRNA pathway to Parkinson's disease.

Original languageEnglish (US)
Pages (from-to)127-130
Number of pages4
JournalJournal of Chemical Neuroanatomy
Volume42
Issue number2
DOIs
StatePublished - Oct 2011

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Keywords

  • MicroRNA
  • Neurodegenerative diseases
  • Parkinson's disease
  • RNA induced silencing
  • Small noncoding RNA

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience

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