Micropipette Aspiration of Oocytes to Assess Cortical Tension

Janice P. Evans; Douglas N. Robinson

doi:10.1007/978-1-4939-8603-3_17

Micropipette Aspiration of Oocytes to Assess Cortical Tension

Janice P. Evans, Douglas N. Robinson

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Just as it is important to understand the cell biology of signaling pathways, it is valuable also to understand mechanical forces in cells. The field of mechanobiology has a rich history, including study of cellular mechanics during mitosis and meiosis in echinoderm oocytes and zygotes dating back to the 1930s. This chapter addresses the use of micropipette aspiration (MPA) to assess cellular mechanics, specifically cortical tension, in mammalian oocytes.

Original language	English (US)
Title of host publication	Methods in Molecular Biology
Publisher	Humana Press Inc.
Pages	163-171
Number of pages	9
DOIs	https://doi.org/10.1007/978-1-4939-8603-3_17
State	Published - 2018

Publication series

Name	Methods in Molecular Biology
Volume	1818
ISSN (Print)	1064-3745

Keywords

Cellular mechanics
Meiosis
Mitosis
Signaling pathways

ASJC Scopus subject areas

Molecular Biology
Genetics

Access to Document

10.1007/978-1-4939-8603-3_17

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