TY - JOUR
T1 - Microflora of the urethra in adolescent boys
T2 - Relationships to sexual activity and nongonococcal urethritis
AU - Chambers, Christopher V.
AU - Shafer, Mary Ann
AU - Adger, Hoover
AU - Ohm-Smith, Marilyn
AU - Millstein, Susan G.
AU - Irwin, Charles E.
AU - Schachter, Julius
AU - Sweet, Richard
N1 - Funding Information:
Sexually transmitted diseases have reached epidemic proportions among adolescents. Because of the potential Supported in part by MCH Grant 000978 from the Department of Health and Human Services (C.V.C., H.A.), STD Training Grant T532AI07234; a grant from the Centers for Disease Control, and Academic Senate Committee on Research, Affirmative Action Career Development Awards, and Research Evaluation and Allocation Committee Award, University of California, San Francisco. Submitted for publication July 28, 1985; accepted October 1, 1986. Reprint requests: Christopher V. Chambers, M.D., Department of Family Medicine, Jefferson Medical College, Suite 401, 1015 Walnut St., Philadelphia, PA 19107.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1987/2
Y1 - 1987/2
N2 - Urethral cultures were obtained from 90 adolescent youth, 16 of whom denied previous sexual activity. Among the sexually active boys was a group of 32 with clinically significant pyuria, consistent with the diagnosis of urethritis, on a first-part urinalysis (FPU) specimen. To relate differences in urethral microflora to sexual activity, 42 sexually active patients with a negative FPU were compared with the never sexually active group. The profile of anaerobic, but not aerobic, bacteria isolated from the urethra was related to the presence or absence of previous sexual activity. Mycoplasma species and Ureaplasma urealyticum were isolated from sexually active patients only, and may be markers of sexual activity in adolescent boys. Of the 32 patients with FPU evidence of urethritis, 22 (69%) had cultures positive for Chlamydia trachomatis, and an additional three (9%) had cultures positive for Neisseria gonorrhoeae. The findings in sexually active patients with a positive FPU were otherwise similar to those of sexually active patients without evidence of urethritis. C. trachomatis appears to be the most important agent of urethritis among adolescent boys with a positive FPU.
AB - Urethral cultures were obtained from 90 adolescent youth, 16 of whom denied previous sexual activity. Among the sexually active boys was a group of 32 with clinically significant pyuria, consistent with the diagnosis of urethritis, on a first-part urinalysis (FPU) specimen. To relate differences in urethral microflora to sexual activity, 42 sexually active patients with a negative FPU were compared with the never sexually active group. The profile of anaerobic, but not aerobic, bacteria isolated from the urethra was related to the presence or absence of previous sexual activity. Mycoplasma species and Ureaplasma urealyticum were isolated from sexually active patients only, and may be markers of sexual activity in adolescent boys. Of the 32 patients with FPU evidence of urethritis, 22 (69%) had cultures positive for Chlamydia trachomatis, and an additional three (9%) had cultures positive for Neisseria gonorrhoeae. The findings in sexually active patients with a positive FPU were otherwise similar to those of sexually active patients without evidence of urethritis. C. trachomatis appears to be the most important agent of urethritis among adolescent boys with a positive FPU.
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U2 - 10.1016/S0022-3476(87)80180-4
DO - 10.1016/S0022-3476(87)80180-4
M3 - Article
C2 - 3100755
AN - SCOPUS:0023127186
SN - 0022-3476
VL - 110
SP - 314
EP - 321
JO - The Journal of pediatrics
JF - The Journal of pediatrics
IS - 2
ER -