Microfabrication and self-assembly of 3D microboxes for biomedical applications

Timothy Leong, Hongke Ye, Emma Call, Barjor Gimi, Zaver Bhujwalla, David H. Gracias

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

This paper reports a novel method for fabricating three dimensional (3D) metallic micropatterned boxes by self-assembly of two dimensional (2D) precursors. A 3D micropatterned device has several advantages over its two dimensional (2D) counterpart - a larger surface area to volume ratio, thereby maximizing interactions with the surrounding medium and providing space to mount different electromechanical modules, and a finite volume allowing encapsulation of functional elements. The microboxes can be constructed in different sizes with perforations on either one or on all faces. We demonstrate encapsulation of gels and polymers within the boxes, and release of chemicals by heating. We envision the use of these boxes in cellular encapsulation and remote release of drugs and biological media in-vitro and in-vivo.

Original languageEnglish (US)
Title of host publication19th IEEE International Conference on Micro Electro Mechanical Systems
Pages502-505
Number of pages4
StatePublished - Oct 24 2006
Event19th IEEE International Conference on Micro Electro Mechanical Systems - Istanbul, Turkey
Duration: Jan 22 2006Jan 26 2006

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume2006
ISSN (Print)1084-6999

Other

Other19th IEEE International Conference on Micro Electro Mechanical Systems
Country/TerritoryTurkey
CityIstanbul
Period1/22/061/26/06

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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