Micro- and nanoengineering for stem cell biology: The promise with a caution

Kshitiz, Deok Ho Kim, David J. Beebe, Andre Levchenko

Research output: Contribution to journalReview articlepeer-review

Abstract

Current techniques used in stem cell research only crudely mimic the physiological complexity of the stem cell niches. Recent advances in the field of micro- and nanoengineering have brought an array of in vitro cell culture models that have enabled development of novel, highly precise and standardized tools that capture physiological details in a single platform, with greater control, consistency, and throughput. In this review, we describe the micro- and nanotechnology-driven modern toolkit for stem cell biologists to design novel experiments in more physiological microenvironments with increased precision and standardization, and caution them against potential challenges that the modern technologies might present.

Original languageEnglish (US)
Pages (from-to)399-408
Number of pages10
JournalTrends in Biotechnology
Volume29
Issue number8
DOIs
StatePublished - Aug 2011

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

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