Methylome Alterations "Mark" New Therapeutic Opportunities in Glioblastoma

Research output: Contribution to journalArticle

Abstract

In this issue of Cancer Cell, Sturm et al. report that global DNA methylation patterns in glioblastoma multiforme divide adult and pediatric tumors into subgroups that have characteristic DNA mutations, mRNA profiles, and most importantly, different clinical behaviors. These findings suggest novel opportunities for therapeutics for this dreaded disease.

Original languageEnglish (US)
Pages (from-to)417-418
Number of pages2
JournalCancer Cell
Volume22
Issue number4
DOIs
StatePublished - Oct 16 2012

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Glioblastoma
DNA Methylation
Neoplasms
Pediatrics
Messenger RNA
Mutation
DNA
Therapeutics

ASJC Scopus subject areas

  • Cancer Research
  • Cell Biology
  • Oncology

Cite this

Methylome Alterations "Mark" New Therapeutic Opportunities in Glioblastoma. / Raabe, Eric; Eberhart, Charles G.

In: Cancer Cell, Vol. 22, No. 4, 16.10.2012, p. 417-418.

Research output: Contribution to journalArticle

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