TY - JOUR
T1 - Methylome Alterations "Mark" New Therapeutic Opportunities in Glioblastoma
AU - Raabe, Eric H.
AU - Eberhart, Charles G.
PY - 2012/10/16
Y1 - 2012/10/16
N2 - In this issue of Cancer Cell, Sturm et al. report that global DNA methylation patterns in glioblastoma multiforme divide adult and pediatric tumors into subgroups that have characteristic DNA mutations, mRNA profiles, and most importantly, different clinical behaviors. These findings suggest novel opportunities for therapeutics for this dreaded disease.
AB - In this issue of Cancer Cell, Sturm et al. report that global DNA methylation patterns in glioblastoma multiforme divide adult and pediatric tumors into subgroups that have characteristic DNA mutations, mRNA profiles, and most importantly, different clinical behaviors. These findings suggest novel opportunities for therapeutics for this dreaded disease.
UR - http://www.scopus.com/inward/record.url?scp=84867614474&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84867614474&partnerID=8YFLogxK
U2 - 10.1016/j.ccr.2012.10.001
DO - 10.1016/j.ccr.2012.10.001
M3 - Short survey
C2 - 23079650
AN - SCOPUS:84867614474
SN - 1535-6108
VL - 22
SP - 417
EP - 418
JO - Cancer cell
JF - Cancer cell
IS - 4
ER -