Methylerythritol cyclodiphosphate (MEcPP) in deoxyxylulose phosphate pathway: Synthesis from an epoxide and mechanisms

Youli Xiao, Rodney L. Nyland, Caren L.Freel Meyers, Pinghua Liu

Research output: Contribution to journalArticle


In this communication, we reported another unique IspG-catalyzed transformation, the production of its substrate, MEcPP, from (2R,3R)-4-hydroxy-3-methyl-2,3-epoxybutanyl diphosphate (Epoxy-HMBPP) when reductants are excluded from the reaction mixture.

Original languageEnglish (US)
Pages (from-to)7220-7222
Number of pages3
JournalChemical Communications
Issue number38
StatePublished - Oct 14 2010


ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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