Methylerythritol cyclodiphosphate (MEcPP) in deoxyxylulose phosphate pathway

Synthesis from an epoxide and mechanisms

Youli Xiao, Rodney L. Nyland, Caren L Meyers, Pinghua Liu

Research output: Contribution to journalArticle

Abstract

In this communication, we reported another unique IspG-catalyzed transformation, the production of its substrate, MEcPP, from (2R,3R)-4-hydroxy-3-methyl-2,3-epoxybutanyl diphosphate (Epoxy-HMBPP) when reductants are excluded from the reaction mixture.

Original languageEnglish (US)
Pages (from-to)7220-7222
Number of pages3
JournalChemical Communications
Volume46
Issue number38
DOIs
StatePublished - Oct 14 2010

Fingerprint

Diphosphates
Epoxy Compounds
Reducing Agents
Phosphates
Communication
Substrates
methyl-D-erythritol 2,4-cyclodiphosphate
deoxyxylulose phosphate

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

Methylerythritol cyclodiphosphate (MEcPP) in deoxyxylulose phosphate pathway : Synthesis from an epoxide and mechanisms. / Xiao, Youli; Nyland, Rodney L.; Meyers, Caren L; Liu, Pinghua.

In: Chemical Communications, Vol. 46, No. 38, 14.10.2010, p. 7220-7222.

Research output: Contribution to journalArticle

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