Methods for assessing the biological effects of specific plant components

Jed W Fahey, Beverly A. Clevidence, Robert M. Russell

Research output: Contribution to journalArticle

Abstract

Until very recently, phytonutrient research was the province of natural product chemists and consisted of primarily anecdotal clinical references. In recent years, an extensive set of qualitative and semi-quantitative dietary epidemiologic data has been developed. This developing base of epidemiologic data is now being supplemented by biochemical, mechanistic, and genetic epidemiology of a more quantitative nature. As we seek to understand the mechanisms that explain a large body of epidemiologic evidence, newer laboratory methods continue to be developed. Though there is a continuing need for even more discriminating nutrition epidemiology to drive the basic research in this area forward, the focus of in vitro, animal and clinical (human) studies must continue to be refined, and appropriate biomarkers for chronic and acute (death) disease end-points must be developed.

Original languageEnglish (US)
JournalNutrition Reviews
Volume57
Issue number9 II
StatePublished - Sep 1999

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Plant Structures
epidemiology
Molecular Epidemiology
Phytochemicals
Acute Disease
chemists
Biological Products
Research
laboratory techniques
Molecular Biology
biomarkers
Epidemiology
Biomarkers
nutrition
death
methodology
animals
In Vitro Techniques
Clinical Studies

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Methods for assessing the biological effects of specific plant components. / Fahey, Jed W; Clevidence, Beverly A.; Russell, Robert M.

In: Nutrition Reviews, Vol. 57, No. 9 II, 09.1999.

Research output: Contribution to journalArticle

Fahey, Jed W ; Clevidence, Beverly A. ; Russell, Robert M. / Methods for assessing the biological effects of specific plant components. In: Nutrition Reviews. 1999 ; Vol. 57, No. 9 II.
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