Methodology for assessing the degree of degeneration of the porcine intervertebral discs based on magnetic resonance imaging

Seweryn Lipiński, Katarzyna Jezierska-Woźniak, Aleksandra Habich, Monika Barczewska, Joanna Wojtkiewicz, Piotr Walczak, Wojciech Maksymowicz

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Degeneration of intervertebral discs can lead to various health problems, among which low back pain is the most common. Studies concerning methods of dealing with that problem are being conducted and magnetic resonance imaging is one of the most popular methods of assessing their progress. Many of these studies are based on animal models. The paper links these two facts and so it contains the description of methodology that can be used for assessing the degree of degeneration of the porcine intervertebral discs based on scans obtained in MRI study. Proposed method uses Otsu method of automatic thresholding and next basic operators of morphological image processing. The outcome is binary mask giving direct information about locations of intervertebral discs in MRI scans. The obtained mask can be also used to separate locations of intervertebral discs in following MRI studies of the same animals, in cases where they are much harder to delineate due to their degeneration. The paper shows also exemplary results demonstrating usefulness of proposed methodology for the evaluation of discs treatment using mesenchymal stem cells.

Original languageEnglish (US)
Title of host publication1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food and Environmental Technologies, WC 2015
EditorsPeter Kramar, Tomaž Jarm
PublisherSpringer Verlag
Pages399-402
Number of pages4
ISBN (Print)9789812878168
DOIs
StatePublished - Jan 1 2016
Event1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food and Environmental Technologies, WC 2015 - Portoroz, Slovenia
Duration: Sep 6 2015Sep 10 2015

Publication series

NameIFMBE Proceedings
Volume53
ISSN (Print)1680-0737

Other

Other1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food and Environmental Technologies, WC 2015
CountrySlovenia
CityPortoroz
Period9/6/159/10/15

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Keywords

  • Animal model
  • Intervertebral discs degeneration
  • Magnetic resonance imaging
  • Morphological image processing

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

Cite this

Lipiński, S., Jezierska-Woźniak, K., Habich, A., Barczewska, M., Wojtkiewicz, J., Walczak, P., & Maksymowicz, W. (2016). Methodology for assessing the degree of degeneration of the porcine intervertebral discs based on magnetic resonance imaging. In P. Kramar, & T. Jarm (Eds.), 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food and Environmental Technologies, WC 2015 (pp. 399-402). (IFMBE Proceedings; Vol. 53). Springer Verlag. https://doi.org/10.1007/978-981-287-817-5_87