Method to evaluate the collagenous microstructure of skin

Stephen M Belkoff, R. C. Haut

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A microstructurally based model for soft biological tissues was adapted to model the nonlinear response of the collagen network in skin. Quasi-static uniaxial tensile tests were conducted on dorsal skin of rats aged 1-4 months. Specimens were taken longitudinally and transversely to the spine and tested at 1.5%/s. The stiffness and microstructural organization of the collagenous network are reported and discussed with respect to biochemical and morphological observations. The model was found to be a convenient and objective way of quantifying the nonlinear response of skin. The model was also found to be sensitive to changes in the microstructure of skin due to age and specimen orientation.

Original languageEnglish (US)
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
EditorsSteven A. Goldstein
PublisherPubl by ASME
Pages13-16
Number of pages4
Volume17
StatePublished - 1990
Externally publishedYes
EventWinter Annual Meeting of the American Society of Mechanical Engineers - Dallas, TX, USA
Duration: Nov 25 1990Nov 30 1990

Other

OtherWinter Annual Meeting of the American Society of Mechanical Engineers
CityDallas, TX, USA
Period11/25/9011/30/90

Fingerprint

Skin
Microstructure
Collagen
Rats
Stiffness
Tissue

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Belkoff, S. M., & Haut, R. C. (1990). Method to evaluate the collagenous microstructure of skin. In S. A. Goldstein (Ed.), American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 17, pp. 13-16). Publ by ASME.

Method to evaluate the collagenous microstructure of skin. / Belkoff, Stephen M; Haut, R. C.

American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. ed. / Steven A. Goldstein. Vol. 17 Publ by ASME, 1990. p. 13-16.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Belkoff, SM & Haut, RC 1990, Method to evaluate the collagenous microstructure of skin. in SA Goldstein (ed.), American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. vol. 17, Publ by ASME, pp. 13-16, Winter Annual Meeting of the American Society of Mechanical Engineers, Dallas, TX, USA, 11/25/90.
Belkoff SM, Haut RC. Method to evaluate the collagenous microstructure of skin. In Goldstein SA, editor, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 17. Publ by ASME. 1990. p. 13-16
Belkoff, Stephen M ; Haut, R. C. / Method to evaluate the collagenous microstructure of skin. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. editor / Steven A. Goldstein. Vol. 17 Publ by ASME, 1990. pp. 13-16
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