Method to evaluate the collagenous microstructure of skin

S. M. Belkoff, R. C. Haut

Research output: Contribution to conferencePaperpeer-review

Abstract

A microstructurally based model for soft biological tissues was adapted to model the nonlinear response of the collagen network in skin. Quasi-static uniaxial tensile tests were conducted on dorsal skin of rats aged 1-4 months. Specimens were taken longitudinally and transversely to the spine and tested at 1.5%/s. The stiffness and microstructural organization of the collagenous network are reported and discussed with respect to biochemical and morphological observations. The model was found to be a convenient and objective way of quantifying the nonlinear response of skin. The model was also found to be sensitive to changes in the microstructure of skin due to age and specimen orientation.

Original languageEnglish (US)
Pages13-16
Number of pages4
StatePublished - Dec 1 1990
EventWinter Annual Meeting of the American Society of Mechanical Engineers - Dallas, TX, USA
Duration: Nov 25 1990Nov 30 1990

Other

OtherWinter Annual Meeting of the American Society of Mechanical Engineers
CityDallas, TX, USA
Period11/25/9011/30/90

ASJC Scopus subject areas

  • Engineering(all)

Fingerprint Dive into the research topics of 'Method to evaluate the collagenous microstructure of skin'. Together they form a unique fingerprint.

Cite this