Abstract
IPMNs of the pancreas are precursor lesions to pancreatic ductal adenocarcinoma. The risk of malignancy in IPMN is based on further subclassification into three types: main-duct IPMN (MD-IPMN), branch-duct IPMN (BD-IPMN), and mixed-type IPMN (MT-IPMN). The malignant potential of MD and MT is substantial and most should undergo resection. The BD-IPMN subtype is more indolent and the decision to resect is more selective. The international consensus guidelines for the management of cystic neoplasms known as the Sendai criteria or Tanaka criteria provide recommendations for the management of BD-IPMN based on risk of malignancy. Indications for resection of BD-IPMN include the high-risk stigmata of jaundice and the presence of a solid component. Since the decision to resect IPMN is based on concern for malignancy, a formal oncological operation should be performed. The outcome of resected benign BD-IPMN is good. However, the risk of progressive or new IPMN disease, including invasive cancer, in patients undergoing resection of BD-IPMN is significant, and these individuals need to be followed closely and indefinitely.
Original language | English (US) |
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Title of host publication | Intraductal Papillary Mucinous Neoplasm of the Pancreas |
Publisher | Springer Japan |
Pages | 163-169 |
Number of pages | 7 |
Volume | 9784431544722 |
ISBN (Electronic) | 9784431544722 |
ISBN (Print) | 4431544712, 9784431544715 |
DOIs | |
State | Published - Nov 1 2014 |
Keywords
- Branch-duct IPMN (BD-IPMN)
- Indications for surgery
- International consensus guidelines
- Invasive IPMN
- Management
- Pancreatic ductal adenocarcinoma
- Sendai criteria
- Tanaka criteria
ASJC Scopus subject areas
- General Medicine