@article{226f3fdea8d74195b79664f246d424aa,
title = "Method for Successfully Inducting Individuals Who Use Illicit Fentanyl Onto Buprenorphine/Naloxone",
abstract = "Background and Objectives: Individuals exposed to fentanyl are at risk of precipitated withdrawal using typical buprenorphine/naloxone induction procedures. Methods: This case series describes buprenorphine/naloxone inductions of four individuals who tested positive for fentanyl. Results: Buprenorphine-precipitated withdrawal was observed in two individuals who completed a conventional buprenorphine/naloxone induction strategy. Two more individuals completed a revised buprenorphine/naloxone induction strategy that did not precipitate withdrawal. Discussion and Conclusion: Using multiple 2 mg doses of buprenorphine/naloxone in patients already in mild/moderate withdrawal improved outcomes. Scientific Significance: Persons who use illicit fentanyl might be less likely to experience precipitated withdrawal from this revised buprenorphine/naloxone induction strategy. (Am J Addict 2021;30:83–87).",
author = "Denis Antoine and Huhn, {Andrew S.} and Strain, {Eric C.} and Gavin Turner and Jasmyne Jardot and Hammond, {Alexis S.} and Dunn, {Kelly E.}",
note = "Funding Information: A.S.Hu receives research funding from Ashley Addiction Treatment through his university. In the past 3 years, K.E.D. has served as a consultant for Beckley Canopy Therapeutics, Canopy Therapuetics, and Gr{\"u}nenthal. E.C.S. has served on advisory boards, received grant funding from, and/or consulted for Alkermes, Analgesic Solutions, Caron, Indivior Pharmaceuticals, Innocoll Pharmaceuticals, The Oak Group/VitalHub, UpToDate, Otsuka Pharmaceutical Development and Commercialization, and Pinney Associates. He has received honoraria from the World Health Organization, and is currently collaborating with Innovative Health Solutions. All other authors report no financial disclosures. Funding Information: ). The work described in this manuscript was funded by the National Institute on Drug Abuse, Bethesda, MD: NIDA UG3DA048734 (A.S.Hu Publisher Copyright: {\textcopyright} 2020 American Academy of Addiction Psychiatry",
year = "2021",
month = jan,
doi = "10.1111/ajad.13069",
language = "English (US)",
volume = "30",
pages = "83--87",
journal = "American Journal on Addictions",
issn = "1055-0496",
publisher = "Wiley-Blackwell",
number = "1",
}