Methicillin-resistant Staphylococcus caprae in a neonatal intensive care unit

T. L. Ross, E. P. Fuss, S. M. Harrington, M. Cai, T. M. Perl, W. G. Merz

Research output: Contribution to journalArticle

Abstract

Staphylococcus caprae, a hemolytic coagulase-negative staphylococcus that is infrequently associated with humans, was initially detected in specimens from six infants in our neonatal intensive care unit due to phenotypic characteristics common to methicillin-resistant Staphylococcus aureus. These isolates were subsequently identified as S. caprae by the Automated RiboPrinter microbial characterization system. This prompted an 8-month retrospective investigation in our neonatal intensive care unit. S. caprae was the cause of 6 of 18 episodes of coagulase-negative staphylococcal bacteremia, was the most common coagulase-negative staphylococcus recovered from the nares of 6 of 32 infants surveyed in a methicillin-resistant S. aureus surveillance program, and was isolated from 1 of 37 health care providers' hands. Of 13 neonatal intensive care unit isolates tested, all were methicillin resistant and positive for the mecA gene. All 21 isolates were found to be a single strain by Automated RiboPrinter and pulsed-field gel electrophoresis with ApaI or SmaI digestion; ApaI was more discriminating in analyzing epidemiologically unrelated strains than Automated RiboPrinter or electrophoresis with SmaI. These findings extend the importance of S. caprae, emphasize its similarities to methicillin-resistant S. aureus, and demonstrate its ability to persist in an intensive care unit setting.

Original languageEnglish (US)
Pages (from-to)363-367
Number of pages5
JournalJournal of Clinical Microbiology
Volume43
Issue number1
DOIs
StatePublished - Jan 2005

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Methicillin Resistance
Neonatal Intensive Care Units
Staphylococcus
Goats
Coagulase
Methicillin-Resistant Staphylococcus aureus
Pulsed Field Gel Electrophoresis
Bacteremia
Health Personnel
Intensive Care Units
Electrophoresis
Digestion
Hand
Genes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

Cite this

Ross, T. L., Fuss, E. P., Harrington, S. M., Cai, M., Perl, T. M., & Merz, W. G. (2005). Methicillin-resistant Staphylococcus caprae in a neonatal intensive care unit. Journal of Clinical Microbiology, 43(1), 363-367. https://doi.org/10.1128/JCM.43.1.363-367.2005

Methicillin-resistant Staphylococcus caprae in a neonatal intensive care unit. / Ross, T. L.; Fuss, E. P.; Harrington, S. M.; Cai, M.; Perl, T. M.; Merz, W. G.

In: Journal of Clinical Microbiology, Vol. 43, No. 1, 01.2005, p. 363-367.

Research output: Contribution to journalArticle

Ross, TL, Fuss, EP, Harrington, SM, Cai, M, Perl, TM & Merz, WG 2005, 'Methicillin-resistant Staphylococcus caprae in a neonatal intensive care unit', Journal of Clinical Microbiology, vol. 43, no. 1, pp. 363-367. https://doi.org/10.1128/JCM.43.1.363-367.2005
Ross, T. L. ; Fuss, E. P. ; Harrington, S. M. ; Cai, M. ; Perl, T. M. ; Merz, W. G. / Methicillin-resistant Staphylococcus caprae in a neonatal intensive care unit. In: Journal of Clinical Microbiology. 2005 ; Vol. 43, No. 1. pp. 363-367.
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